Swine Flu Is Now Infecting Dogs

H1N1, a flu virus originating from birds and commonly identified as swine flu, has been discovered in dogs from the Guangxi region of China. These animals were brought to the vet after showing symptoms consistent with canine influenza, and researchers published their analysis of the 16 strains of flu they found. The most notable discovery was H1N1, the swine flu strain responsible for the 2009 pandemic that resulted in more than 200,000 deaths. Study co-author Adolfo García-Sastre, director of the Global Health and Emerging Pathogens Institute at the Icahn School of Medicine at Mount Sinai in New York, says there is a reason to be cautious.

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In our study, what we have found is another set of viruses that come from swine that are originally avian in origin, and now they are jumping into dogs and have been reassorted with other viruses in dogs. We now have H1N1, H3N2, and H3N8 in dogs. They are starting to interact with each other. This is very reminiscent of what happened in swine ten years before the H1N1 pandemic.”

Adaptable Influenza

The continuing battle to correctly guess the dominant flu strain of the season showcases how adaptive and varied the flu is. Often pandemics originate in animals, usually birds or swine. While dogs have never been considered a significant carrier of the virus, more varied and potentially strains have been showing up in canine tests. The potential for a devastating flu pandemic that we aren’t prepared for is high in man’s best friend. There have been documented instances of viruses from avian, porcine, and equine sources successfully jumping to dogs, and that’s a potential flu cocktail that humans don’t have immunity against.

Can It Affect Us?

Does that even matter? There is no case of a human ever being infected by canine flu.

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Humans have previously been infected by the strain of flu found in the dogs, H1N1, but previous exposure has come from birds, who were the original carriers. Of course, H1N1 is now more closely identified with pigs, after 2009 swine flu outbreak. H1N1 became the dominant strain of flu in 1998, and the virus was seriously affecting humans within ten years. Before then, the idea that humans would be suffering from swine flu was farfetched.

It’s important to note that vaccination efforts were unsuccessful in both pigs and humans, primarily due to how fast the virus evolves. H1N1 also showed resistance to Tamiflu, the controversial antiviral drug. Healthcare professionals in the U.S. ended up using vaccines nearly identical to the seasonal flu vaccine, which is a daunting prospect in light of how poorly that immunization performed this year. If the discovery of an adaptable H1N1 virus in dogs follows the same trajectory as H1N1 did in pigs, do we have any good solutions?  In cases of avian flu, farmers eliminate diseased birds from the flock immediately. Is that even an option when many Americans consider their dog a member of the family?

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The More You Know

Scientists repeatedly mention how diverse canine flu strains are becoming, and there isn’t a push to figure out why. Perhaps part of the answer is the proximity of the animals to the ultimate disease incubators – us.

The further we continue down the rabbit hole of our health care system, the more it becomes clear that we have dramatically underestimated our opponents. Our answers to the problems posed by bacteria and viruses have seemed to inspire those pathogens to greater and more creative heights at a speed not seen in nature.

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Breast Cancer, Unnecessary Chemotherapy, and Invasive Procedures for Women

Is it easier to prescribe exhausting, and ineffective medications than it is to look for actual disease prevention and treatment? The answer is yes, and sixty percent of women with breast cancer are paying the price for that complacency with unnecessary chemotherapy.

A recent study released in the New England Journal of Medicine examined outcomes from two different breast cancer treatments: hormone therapy, and chemotherapy. After nine years of following patients, researchers found that the results were indistinguishable. It didn’t matter what treatment they received – nine out of ten women survived. So why do we continue with chemotherapy?

Do the ends justify the means?

Chemotherapy is our default medical standard of care for cancer. While it can eliminate the immediate threat, it’s more problematic than helpful. The cancer is gone, but many women are left crippled in another way. The immune system is a shell of what it once was, leaving the body open to all manner of infections and other health conditions.  According to Otis Brawley, chief medical and scientific officer for the American Cancer Society,

I have lost three patients over the last 25 years because they got leukemia from their chemo…I have lost patients who got congestive heart failure because of their chemo, and I have seen patients who get ‘chemo brain’ and have difficulty concentrating for the rest of their lives.”

The other, less invasive treatment option presented in this article isn’t perfect. Endocrine therapy, which inhibits the body’s ability to produce estrogen, can result in symptoms of early menopause, joint pain, and weight loss. But we didn’t have that option until recently. Why not? Is chemotherapy so effective that medicine should have stopped looking for solutions?

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It’s a Pattern

The practice of applying unnecessarily invasive treatments to an entire gender is not a new one in the United States. The World Health Organization has advocated for a c-section rate of 10-15% for over 30 years. Yet the U.S. is frequently cited for rates of more than double that. C-sections are among the most performed surgeries in the U.S., yet mothers who fight for a different outcome are constantly told that “the most important thing is a healthy baby.” Yes, this is true, but that should not be a reason to discourage informed women trying to minimize the physiological fallout from pregnancy. There is a reason the percentage of expectant mothers who find it necessary to hire a doula when giving birth has doubled in a six-year period. Having an advocate is more important than ever.

Me Too

Studies have found that doctors are less likely to listen to or take the concerns of female patients seriously, sometimes describing their pain as emotional or psychogenic. Yet that lack of engagement can lead to treating all women with one size all procedures that aren’t always necessary. It also causes many women years of frustration, searching for someone who will take their concerns seriously.

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It’s ironic that the alternative treatment to chemotherapy examined in this study reduces the amount estrogen in the body, literally suppressing female hormones. Women are taught to avoid rocking the boat, but speaking up or voting with your dollar and finding someone who will listen can be the thing that saves you from potential long-lasting health issues.

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CRISPR Edited Cells May Cause Cancer According to Two Studies

Gene editing changes an organism’s DNA. The technology allows genetic material inside a cell to be added, removed, or altered at specific locations within the genome.  Many different gene editing technologies have been developed, including CRISPR-Cas9, short for “clustered regularly interspaced short palindromic repeats and CRISPR-associated protein 9.” This gene editing method has generated tons of excitement in the scientific community because it was believed to be faster, less expensive, and much more accurate than other existing genome editing methods.

CRISPR-Cas9 was a much-hyped gene editing tool that was going to be a breakthrough for medicine. A Newsweek title read, “…Could Stop Cancer, Diabetes and Bioterrorism.” But there’s a problem. Editing a cell’s genomes with CRISPR-Cas9 could have unintended consequences. According to two studies published in Nature Medicine, the CRISPR-Cas9 edited cells may seed tumors inside a patient. Those same cells that were intended to treat disease could be triggering cancer. Even though the stocks tanked upon the news, researches don’t want to sound the alarm bells. Bernhard Schmierer, a researcher with the Karolinska Institutet, said that CRISPR-Cas9 is a “powerful tool with staggering therapeutic potential,” before he went into possible risks,

Like all medical treatments however, CRISPR-Cas9-based therapies might have side effects, which the patients and caregivers should be aware of. Our study suggests that future work on the mechanisms that trigger p53 in response to CRISPR-Cas9 will be critical in improving the safety of CRISPR-Cas9-based therapies.”

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Dr. Emma Haapaniemi, a researcher at the Department of Medicine, Huddinge, Karolinska Institutet and co-first author of the study stated,

By picking cells that have successfully repaired the damaged gene we intended to fix, we might inadvertently also pick cells without functional p53. If transplanted into a patient, as in gene therapy for inherited diseases, such cells could give rise to cancer, raising concerns for the safety of CRISPR-based gene therapies.”

P53 mutations are responsible for nearly half of ovarian cancers; 43 percent of colorectal cancers; 38 percent of lung cancers; nearly one-third of pancreatic, stomach, and liver cancers; and one-quarter of breast cancers, among others.” – STAT

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TransCanada Natural Gas Pipeline Exploded In West Virginia

A newly installed TransCanada natural gas pipeline exploded last Thursday morning in the remote Nixon Ridge area of Marshall County in West Virginia, sending a ball of fire shooting up into the sky. People as far away as Washington County reported seeing flames. WTOV-TV states that the explosion occurred in a TransCanada pipeline. No injuries have been reported.

It sounded like a freight train coming through, or a tornado, and the sky lit up bright orange, and then I got up and looked out the window and flames were shooting I don’t know how far into the sky.” – Tina Heath-Chaplin, of Moundsville

WTOV-TV in Steubenville, Ohio, reported that the explosion happened on June 7th shortly before 4:30 a.m.

Area police told CBS News “…if you can see it from your house, evacuate,” but reports showed that the flames could be seen from at least 20 miles away.

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TransCanada is the company behind the infamous Keystone pipeline. Shortly after the explosion, the company stated that the situation had been contained.

As soon as the issue was identified, emergency response procedures were enacted and the segment of impacted pipeline was isolated. The fire was fully extinguished by approximately 8:30 a.m.”

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https://www.facebook.com/ruby.mason.54/videos/1587635261364082/

This pipeline is the Leach XPress. It was put into service January 1, 2018. TransCanada emphasized that the pipeline was built very quickly, but also safely.

We’re looking forward to generations of safe operations. This is truly a best-in-class pipeline and we look forward to many years of safe, reliable, and efficient operation on behalf of our customers.” – ” Scott Castleman, manager of U.S. Gas Communications for TransCanada

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Monsanto’s Name To Be Retired – Bayer Aims To Erase Sordid History

Now that the merger between Bayer and Monsanto has been approved, the German pharmaceutical giant has announced plans to scrub the Monsanto name from their agrochemical products, selling them under the name Bayer Crop Science instead. After receiving the U.S. government approval for the merger, the company announced,

Bayer will remain the company name. Monsanto will no longer be a company name. The acquired products will retain their brand names and become part of the Bayer portfolio…”

The deal is scheduled to be completed on June 14.

The Benefits

In eliminating the name Monsanto, Bayer is getting rid of quite a bit of baggage. Monsanto is responsible for the introduction of several products that have done serious damage to the environment and public health, like Agent Orange, polychlorinated biphenyls (PCBs), saccharin, aspartame, and recently designated carcinogen, glyphosate. Entire protest movements are dedicated to opposing Monsanto, and there’s always the possibility that the more stringent regulations of GMOs have been in response to their reputation. With this move, Bayer loses the liability of the Monsanto reputation while maintaining Monsanto’s profits and market control.

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https://www.youtube.com/watch?v=8-EW4XzQwRM

Holistic Profits

Bayer is remaking itself. Originally a pharmaceutical company, they’re now moving into agriculture. But not just any agriculture…they’re getting into agriculture with a company that has been definitively linked to making people sick. Which makes this an excellent move for Bayer. Step one, take control of the food system. Step two, make the food that causes cancer and disrupts the endocrine system impossible to avoid. Step three, sell the drugs needed to manage the conditions caused by unavoidable unhealthy food. Step four? Profit, clearly.

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Puget Sound Mussels Contain Opioids, Antidepressants, and Chemotherapy Drugs

The biannual Puget Sound mussel monitoring study found that three of eighteen samples of native bay mussels contained trace amounts of oxycodone, the chemotherapy drug Melphalan, and antidepressants. Scientists from the Washington Department of Fish and Wildlife (WDFW) transplant uncontaminated mussels to various locations in the Seattle and Bremerton harbors and check them two to three months later. It is not unusual for pharmaceuticals and illegal drugs like cocaine to be found during these surveys, but this is the first time scientists have found opioids. Jennifer Lanksbury is a biologist at the WDWW.

What we eat and what we excrete goes into the Puget Sound…It’s telling me there’s a lot of people taking oxycodone in the Puget Sound area.”

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How Do They Get There?

Opioid use in the U.S. has spiraled out of control, with deaths from pharmaceutical versions, heroin, and fentanyl nearly tripling since 2002. Finding evidence of that crisis in our waterways is a when, not an if. But how does that happen?

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The biggest culprits are wastewater plants discharging into the bay. Opioids enter the waste stream through human excrement and improperly disposed of pharmaceuticals (flushing them). An earlier study in the Great Lakes found that wastewater treatment facilities were only able to remove half of the prescription drugs that enter the plant. A quarter of chemicals had low removal rates, where there was less than 25 percent chance of removing 75 percent or more of the drug. Runoff from agricultural sources is also a contributor to the presence of harmful chemicals in aquatic environments.

What Do the Fish Think?

The bay mussels are not likely to metabolize these opioids, especially in the trace amounts found, but what about other fish? Zebrafish, although not a resident of the Puget Sound, learn how to dose themselves with opioids, and scientists surmise that salmon and other native species will have similar reactions. The effects of these drugs on the aquatic population will likely be more clear as the opioid crisis continues to gain momentum.

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The opioids were found in trace amounts, but the chemotherapy drug Melphalan was found in doses that correspond to a recommended dose in humans. This drug interacts with DNA and is a carcinogen. The National Institutes of Health notes that

…There is sufficient evidence for the carcinogenicity of melphalan from studies in experimental animals. When administered by intraperitoneal injection, melphalan caused cancer of lymphatic tissue (lymphosarcoma) in male mice, lung tumors in mice of both sexes, and cancer of the abdominal cavity (sarcoma of the peritoneum) in rats of both sexes…”

Water At Risk

Water is our most precious resource, and we have not been good stewards of it. The ecosystem that keeps our bodies of water and our very planet healthy is constantly being changed and manipulated without a way to correct for the changes. This is the first evidence of opioids in the water, but other drugs have become commonplace as we see with the Melphalan. There are no procedures in place to keep the same thing from happening with opioids.

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Bayer Monsanto Merger Gets U.S. Approval, Conquering Last Regulatory Hurdle

Last Tuesday Bayer AG received U.S. antitrust approval to takeover Monsanto, clearing the last major regulatory hurdle for the 66 billion dollar deal to happen. The deal has received antitrust approval from most jurisdictions around the world. Bayer is still waiting for Mexico and Canada’s approval, but according to a recent statement, the company believes the deal will close by the June 14 deadline. If the deal is not completed by June 14 Monsanto could pull out or seek a higher price.

Approval from the U.S. Justice Department is contingent on the sale of $9 billion in Bayer assets to BASF. The sales of those assets include the Liberty herbicide brand as well as the company’s canola, soybean, and vegetable seed businesses. These products compete with current Monsanto products.

Makan Delrahim, head of the Justice Department’s Antitrust Division, says that this is the largest divestiture in U.S. antitrust enforcement history.

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Acquiring Monsanto is the latest move in a series of steps to transform the 154-year-old company. Bayer used to be a plastics business. Now they are considered a “life-science” company. Bayer will be equal parts health industry and agriculture industry.

When the deal goes through there will be three massive global corporations that control the world’s agriculture industry: DowDuPont, Syngenta AG, and Bayer-Monsanto.

The DOJ’s weak divestment requirements will do nothing to stop Bayer-Monsanto from controlling more and more of our food system. This merger will damage the bargaining power of family farmers, prevent farmers from accessing diverse seed varieties, and allow seed prices to rise.” – Tiffany Finck-Haynes, senior food futures campaigner with Friends of the Earth via Bloomerg

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