A new study, reported in JAMA Psychiatry, found Psilocybin to be four times more effective at treating depression, compared to antidepressants. Psilocybin is the psychedelic substance in magic mushrooms. This research comes after research suggesting that psilocybin could ease depression and anxiety in cancer patients.

The study involved 27 people. Patients received two doses of psilocybin on two different days, in addition to 11 hours of psychotherapy. Patients were administered the drug in what Alan Davis, lead author on the study, describes as a homey but safe environment. After being administered the drug, patients were blindfolded and given headphones, and told experience whatever was happening within the trip. Half of the patients were put on a waitlist to serve as a comparison group for the other half of the group, who began treatment immediately.

The group who began treatment immediately saw a significant reduction in depression and responded much quicker compared to antidepressants.

“The effect happened within one day after the first session and sustained at that reduced level through the second psilocybin session all the way up to the one-month follow-up,”

Rigorous Study Backs A Psychedelic Treatment For Major Depression

Denver has approved the grassroots ordinance 301 to decriminalize psilocybin mushrooms (aka psychedelic mushrooms).

It looked like the initiative would be a failed effort but it narrowly passed. It with 50.56% voting in favor of decriminalization.

Psilocybin mushrooms won’t be legal in Denver, but once the ordinance goes into effect the city will not be criminally prosecuting or arresting adults for possession, as long as they are 21 or more years old. The ballot also allows for growing the mushrooms for personal use. The initiative is expected to take effect sometime next year.

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What happened in Denver may be the start of a much larger movement, which seeks safe access to psilocybin for its purported medicinal value. Supporters point to research, suggesting psilocybin is not addictive and causes few ER visits compared to other illegal drugs. Ongoing medical research shows it could be a groundbreaking medicine for treatment-resistant depression and to help curb nicotine addiction.

NPR

Republican congressman Jeff Shipley, in Iowa, has proposed to legalize the medicinal use of psilocybin mushrooms, MDMA, and ibogaine. Oregon and California also have campaigns legalize psilocybin mushrooms for the 2020 elections.

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Psilocybin mushrooms classified under federal law as a Schedule 1 drug. NPR reports that DEA officials in Denver say they will still prosecute for psilocybin possession and trafficking.